Assay Report Card

Basic Information

ID: ALA4707271

Type: Functional

Description: In vivo inhibition of HDAC in BALB/c mouse xenografted with human MV4-11 cells assessed as increase in acetylation of histone H3 at K9 residue in tumor tissue at 25 mg/kg, iv measured after 1 hr by Western blot analysis

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
440.511.761.76