Basic Information
ID: ALA4707276
Type: ADME
Description: Metabolic stability in human liver pooled microsomes assessed as half-life at 5 uM incubated upto 60 mins in presence of beta-NADPH by LC-MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4707276
t1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 264.32 | 2.47 | 2.47 |
| 271.40 | 3.38 | 3.38 |
| 508.56 | 2.14 | 2.14 |
| 464.53 | 2.66 | 2.66 |
| 440.51 | 1.76 | 1.76 |
| 530.59 | 2.04 | 2.04 |
| 455.52 | 2.19 | 2.19 |
| 454.53 | 2.28 | 2.28 |
| 484.56 | 2.16 | 2.16 |
| 414.47 | 1.51 | 1.51 |
| 440.51 | 1.76 | 1.76 |
| 441.50 | 1.16 | 1.16 |
| 456.51 | 1.58 | 1.58 |