Basic Information
ID: ALA4707448
Type: Functional
Description: Biased agonist activity at human recombinant 5-HT1A receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after 40 mins by LANCE Ultra cAMP kit-based TR-FRET assay relative to serotonin
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA4707448
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 176.22 | 1.37 | 1.37 |
| 385.51 | 2.09 | 2.09 |
| 247.38 | 3.37 | 3.37 |
| 394.85 | 3.31 | 3.31 |
| 408.88 | 3.52 | 3.52 |
| 408.88 | 4.09 | 4.09 |
| 409.86 | 3.49 | 3.49 |
| 424.88 | 3.19 | 3.19 |
| 409.86 | 3.49 | 3.49 |
| 410.85 | 2.88 | 2.88 |
| 406.90 | 4.65 | 4.65 |
| 426.32 | 4.00 | 4.00 |
| 425.93 | 4.20 | 4.20 |
| 407.89 | 4.04 | 4.04 |
| 407.89 | 4.13 | 4.13 |
| 424.94 | 4.81 | 4.81 |