Basic Information
ID: ALA4707861
Type: Binding
Description: Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of europium-labeled co-activator SRC1 recruitment incubated for 1 hr by FRET assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4707861
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.60 | 3.24 | 3.24 |
| 470.64 | 2.92 | 2.92 |
| 518.68 | 4.15 | 4.15 |
| 442.59 | 2.48 | 2.48 |
| 460.58 | 2.62 | 2.62 |
| 477.03 | 3.14 | 3.14 |
| 427.57 | 2.68 | 2.68 |
| 456.61 | 2.79 | 2.79 |
| 427.57 | 2.63 | 2.63 |
| 534.75 | 3.20 | 3.20 |
| 467.60 | 2.36 | 2.36 |
| 477.03 | 3.14 | 3.14 |
| 548.78 | 3.59 | 3.59 |
| 521.68 | 5.64 | 5.64 |
| 510.58 | 3.50 | 3.50 |
| 456.61 | 2.79 | 2.79 |
| 413.54 | 2.64 | 2.64 |
| 457.64 | 3.95 | 3.95 |
| 456.61 | 2.79 | 2.79 |
| 526.58 | 3.38 | 3.38 |
| 477.03 | 3.14 | 3.14 |
| 507.66 | 5.56 | 5.56 |
| 498.69 | 3.78 | 3.78 |
| 413.54 | 2.64 | 2.64 |
| 399.52 | 2.25 | 2.25 |
| 460.58 | 2.62 | 2.62 |
| 399.52 | 2.20 | 2.20 |