Basic Information
ID: ALA4707890
Type: Binding
Description: Inhibition of recombinant human LSD1 (157 to 852 residues) expressed in Escherichia coli BL21 (DE) cells at 20 uM using H3K4me2 substrate incubated for 30 mins by amplex red assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Lysine-specific histone demethylase 1(ALA6136)
Document: ALA4706492
Inhibition of recombinant human LSD1 (157 to 852 residues) expressed in Escherichia coli BL21 (DE) cells at 20 uM using H3K4me2 substrate incubated for 30 mins by amplex red assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4707890
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 540.68 | 4.11 | 4.11 |
| 442.62 | 3.83 | 3.83 |
| 540.72 | 5.35 | 5.35 |
| 484.68 | 4.02 | 4.02 |
| 454.59 | 3.36 | 3.36 |
| 460.59 | 2.99 | 2.99 |
| 512.67 | 4.55 | 4.55 |
| 517.69 | 4.44 | 4.44 |
| 485.04 | 4.74 | 4.74 |
| 450.60 | 4.09 | 4.09 |
| 389.51 | 2.00 | 2.00 |
| 439.57 | 3.16 | 3.16 |
| 339.43 | 0.72 | 0.72 |
| 401.50 | 1.56 | 1.56 |
| 423.50 | 2.99 | 2.99 |
| 403.54 | 1.68 | 1.68 |
| 423.95 | 2.66 | 2.66 |
| 353.48 | 0.67 | 0.67 |
| 387.47 | 2.15 | 2.15 |
| 423.95 | 2.66 | 2.66 |
| 468.41 | 2.77 | 2.77 |
| 423.95 | 2.66 | 2.66 |
| 419.54 | 2.01 | 2.01 |
| 407.89 | 2.49 | 2.49 |
| 390.50 | 1.40 | 1.40 |
| 390.50 | 1.40 | 1.40 |
| 355.49 | 0.89 | 0.89 |
| 365.42 | 1.65 | 1.65 |