Inhibition of CYP3A4 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and meas...

Basic Information

ID: ALA4708313

Type: ADME

Description: Inhibition of CYP3A4 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and measured after 30 mins by fluorescence based analysis

Format: BAO_0000357

Organism: Homo sapiens

Target: Cytochrome P450 3A4(ALA340)

Document: ALA4706503

Inhibition of CYP3A4 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and measured after 30 mins by fluorescence based analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4708313

IC50

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
151.16	1.35	1.35
485.52	1.69	1.69
363.39	0.67	0.67

Parent Molecular Weight

ALogP

Polar Surface Area

151.16

1.35

485.52

1.69

363.39

0.67

Inhibition of CYP3A4 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and meas...

Basic Information

Activity Charts

Compound Summary