Assay Report Card

Basic Information

ID: ALA4708327

Type: Binding

Description: Inhibition of Kaposi's sarcoma herpesvirus wild type LANA CTD (934 to 1162 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of LANA interaction with 5'-Dy682-labeled viral DNA LBS1 probe at 250 uM preincubated with LANA CTD for 60 mins followed by addition of DNA probe and measured after 30 mins by Electrophoretic mobility shift assay

Organism: Human gammaherpesvirus 8

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.262.032.03
350.773.833.83
358.363.823.82
376.804.354.35
342.363.693.69
386.413.503.50
372.383.713.71
330.353.493.49