Basic Information
ID: ALA4708485
Type: Binding
Description: Inhibition of wild type IDH2 (unknown origin) assessed as reduction in NADPH production using sodium(D)-isocitrate and NADP as substrate preincubated with enzyme for 15 mins followed by substrate addition by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4708485
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.38 | 4.29 | 4.29 |
| 510.49 | 7.02 | 7.02 |
| 468.41 | 5.85 | 5.85 |
| 444.46 | 4.77 | 4.77 |
| 510.44 | 5.64 | 5.64 |
| 540.51 | 6.65 | 6.65 |
| 446.41 | 4.38 | 4.38 |
| 494.44 | 6.41 | 6.41 |
| 466.39 | 5.63 | 5.63 |
| 482.43 | 6.24 | 6.24 |
| 482.39 | 5.47 | 5.47 |
| 512.46 | 6.11 | 6.11 |
| 472.39 | 4.90 | 4.90 |
| 528.46 | 5.70 | 5.70 |
| 444.46 | 5.09 | 5.09 |
| 524.47 | 6.03 | 6.03 |
| 512.46 | 5.87 | 5.87 |
| 442.45 | 4.55 | 4.55 |
| 508.47 | 6.80 | 6.80 |
| 496.46 | 6.63 | 6.63 |
| 512.41 | 5.47 | 5.47 |
| 448.42 | 4.60 | 4.60 |
| 497.40 | 4.65 | 4.65 |
| 498.43 | 5.48 | 5.48 |
| 496.42 | 5.86 | 5.86 |
| 484.40 | 5.69 | 5.69 |
| 526.49 | 6.26 | 6.26 |
| 405.38 | 3.27 | 3.27 |
| 462.86 | 4.89 | 4.89 |
| 404.40 | 3.88 | 3.88 |
| 498.43 | 6.08 | 6.08 |
| 496.42 | 5.26 | 5.26 |
| 480.42 | 6.02 | 6.02 |
| 464.88 | 5.11 | 5.11 |