Basic Information
ID: ALA4708492
Type: Binding
Description: Inhibition of human IDH2 R140Q mutant expressed in TF-1 cells assessed as inhibition of 2-HG production at 10 uM incubated for 48 hrs by LC-MS/MS analysis
Organism: Homo sapiens
Cell type: TF-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4708492
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.38 | 4.29 | 4.29 |
| 510.49 | 7.02 | 7.02 |
| 468.41 | 5.85 | 5.85 |
| 494.44 | 6.41 | 6.41 |
| 466.39 | 5.63 | 5.63 |
| 482.43 | 6.24 | 6.24 |
| 482.39 | 5.47 | 5.47 |
| 512.46 | 6.11 | 6.11 |
| 472.39 | 4.90 | 4.90 |
| 444.46 | 5.09 | 5.09 |
| 512.46 | 5.87 | 5.87 |
| 508.47 | 6.80 | 6.80 |
| 496.46 | 6.63 | 6.63 |
| 498.43 | 5.48 | 5.48 |
| 496.42 | 5.86 | 5.86 |
| 484.40 | 5.69 | 5.69 |
| 526.49 | 6.26 | 6.26 |
| 405.38 | 3.27 | 3.27 |
| 404.40 | 3.88 | 3.88 |
| 498.43 | 6.08 | 6.08 |
| 496.42 | 5.26 | 5.26 |
| 480.42 | 6.02 | 6.02 |