Basic Information
ID: ALA4708695
Type: Binding
Description: Inhibition of recombinant human Prolyl oligopeptidase expressed in Escherichia coli expression system using (Z)-Gly-Pro-p-nitroanilide as substrate preincubated with enzyme for 5 mins followed by substrate addition and measured for 30 mins by spectrophotometric analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Prolyl endopeptidase(ALA3202)
Document: ALA4706517
Inhibition of recombinant human Prolyl oligopeptidase expressed in Escherichia coli expression system using (Z)-Gly-Pro-p-nitroanilide as substrate preincubated with enzyme for 5 mins followed by substrate addition and measured for 30 mins by spectrophotometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4708695
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.82 | 3.10 | 3.10 |
| 492.37 | 4.67 | 4.67 |
| 571.27 | 5.43 | 5.43 |
| 537.37 | 4.57 | 4.57 |
| 571.27 | 5.43 | 5.43 |
| 506.40 | 4.98 | 4.98 |
| 561.26 | 5.97 | 5.97 |
| 542.43 | 5.82 | 5.82 |
| 550.41 | 4.45 | 4.45 |
| 526.81 | 5.32 | 5.32 |
| 560.37 | 5.69 | 5.69 |
| 506.40 | 5.23 | 5.23 |
| 526.81 | 5.32 | 5.32 |
| 506.40 | 4.98 | 4.98 |
| 534.45 | 5.79 | 5.79 |
| 506.40 | 4.98 | 4.98 |
| 537.37 | 4.57 | 4.57 |
| 571.27 | 5.43 | 5.43 |
| 522.40 | 4.68 | 4.68 |
| 522.40 | 4.68 | 4.68 |
| 520.42 | 5.28 | 5.28 |
| 538.46 | 5.39 | 5.39 |
| 517.38 | 4.54 | 4.54 |