Basic Information
ID: ALA4708727
Type: ADME
Description: Prodrug conversion in monkey liver microsomes assessed as formation of (1S,2S,3S,5R,6S)-2-amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylicacid at 3 umol/L after 15 mins by LC-MS/MS analysis
Organism: Macaca mulatta
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4708727
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 203.17 | -0.54 | -0.54 |
| 373.38 | 1.75 | 1.75 |
| 317.31 | 0.46 | 0.46 |
| 373.38 | 1.75 | 1.75 |
| 425.45 | 2.38 | 2.38 |
| 317.31 | 0.46 | 0.46 |
| 429.49 | 2.88 | 2.88 |
| 333.31 | 0.82 | 0.82 |
| 429.49 | 2.88 | 2.88 |
| 315.25 | -0.03 | -0.03 |
| 429.49 | 2.88 | 2.88 |
| 315.25 | -0.03 | -0.03 |
| 335.29 | 0.78 | 0.78 |