Assay Report Card

Basic Information

ID: ALA4709166

Type: Binding

Description: Inhibition of ERCC1-XPF in UV-radiated human HCT-116 cells assessed as cyclobutane pyrimidine dimer DNA repair at 2 uM preincubated for 1 hr followed by 8 J/m2 UV-C radiation and measured up to 24 hrs by IgG-Alexafluor antibody based fluorescent microscopic analysis (Rvb = 16%)

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
506.054.884.88