Basic Information
ID: ALA4709176
Type: Binding
Description: Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition and measured after 20 mins by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4709176
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 320.52 | 6.73 | 6.73 |
| 180.25 | 2.83 | 2.83 |
| 206.28 | 3.07 | 3.07 |
| 194.27 | 3.13 | 3.13 |
| 292.42 | 4.52 | 4.52 |
| 292.46 | 5.95 | 5.95 |
| 208.26 | 2.18 | 2.18 |
| 320.47 | 5.30 | 5.30 |
| 348.53 | 6.08 | 6.08 |
| 194.27 | 3.13 | 3.13 |
| 219.03 | 1.87 | 1.87 |
| 350.54 | 6.74 | 6.74 |
| 294.44 | 5.18 | 5.18 |
| 207.27 | 2.63 | 2.63 |
| 217.02 | 0.95 | 0.95 |
| 322.49 | 5.96 | 5.96 |