Basic Information
ID: ALA4709178
Type: Binding
Description: Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured after 10 mins by ELISA
Format: BAO_0000357
Organism: Homo sapiens
Target: Arachidonate 5-lipoxygenase(ALA215)
Document: ALA4706530
Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured after 10 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4709178
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 206.28 | 3.07 | 3.07 |
| 292.42 | 4.52 | 4.52 |
| 208.26 | 2.18 | 2.18 |
| 320.47 | 5.30 | 5.30 |
| 348.53 | 6.08 | 6.08 |
| 194.27 | 3.13 | 3.13 |
| 219.03 | 1.87 | 1.87 |
| 294.35 | 3.28 | 3.28 |
| 350.54 | 6.74 | 6.74 |
| 261.07 | 1.31 | 1.31 |
| 406.56 | 6.40 | 6.40 |
| 294.44 | 5.18 | 5.18 |
| 207.27 | 2.63 | 2.63 |
| 217.02 | 0.95 | 0.95 |
| 210.27 | 2.84 | 2.84 |
| 322.49 | 5.96 | 5.96 |