Basic Information
ID: ALA4709180
Type: Binding
Description: Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate at 20 uM preincubated with enzyme for 5 mins followed by substrate addition and measured after 20 mins by ELISA relative to control
Format: BAO_0000357
Organism: Ovis aries
Target: Cyclooxygenase-1(ALA2949)
Document: ALA4706530
Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate at 20 uM preincubated with enzyme for 5 mins followed by substrate addition and measured after 20 mins by ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4709180
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 194.27 | 3.13 | 3.13 |
| 348.53 | 6.08 | 6.08 |
| 294.35 | 3.28 | 3.28 |
| 261.07 | 1.31 | 1.31 |
| 406.56 | 6.40 | 6.40 |
| 210.27 | 2.84 | 2.84 |