Basic Information
ID: ALA4709468
Type: Binding
Description: Inhibition of full length recombinant human N-terminal GST/His6-tagged PAK1 expressed in sf9 insect cells using tetra LRRWSLG as substrate preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Serine/threonine-protein kinase PAK 1(ALA4600)
Document: ALA4706541
Inhibition of full length recombinant human N-terminal GST/His6-tagged PAK1 expressed in sf9 insect cells using tetra LRRWSLG as substrate preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4709468
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.64 | 4.53 | 4.53 |
| 518.07 | 5.04 | 5.04 |
| 392.85 | 3.70 | 3.70 |
| 406.87 | 4.09 | 4.09 |
| 285.73 | 3.24 | 3.24 |
| 422.87 | 3.06 | 3.06 |
| 448.91 | 3.82 | 3.82 |
| 432.91 | 4.58 | 4.58 |
| 475.98 | 4.17 | 4.17 |
| 469.93 | 4.67 | 4.67 |
| 378.82 | 3.39 | 3.39 |
| 436.90 | 3.72 | 3.72 |
| 468.94 | 5.27 | 5.27 |
| 432.91 | 4.48 | 4.48 |
| 418.88 | 4.17 | 4.17 |
| 417.90 | 4.79 | 4.79 |
| 476.96 | 4.50 | 4.50 |
| 490.01 | 4.41 | 4.41 |
| 483.96 | 4.71 | 4.71 |
| 416.91 | 5.39 | 5.39 |
| 377.84 | 4.01 | 4.01 |
| 455.91 | 4.99 | 4.99 |
| 462.94 | 4.25 | 4.25 |
| 376.85 | 4.61 | 4.61 |