Basic Information
ID: ALA4709752
Type: Binding
Description: Inhibition of recombinant GST-tagged human CDK2/GST-tagged cyclin E expressed in sf9 cells using biotinylated peptide biotin-Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins followed by ATP and substrate addition and measured after 25 mins by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Cyclin-dependent kinase 2/cyclin E1(ALA1907605)
Document: ALA4706546
Inhibition of recombinant GST-tagged human CDK2/GST-tagged cyclin E expressed in sf9 cells using biotinylated peptide biotin-Ttds-YISPLKSPYKISEG as substrate preincubated for 15 mins followed by ATP and substrate addition and measured after 25 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4709752
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.43 | 4.49 | 4.49 |
| 387.44 | 3.61 | 3.61 |
| 389.41 | 2.22 | 2.22 |
| 404.44 | 4.35 | 4.35 |
| 421.45 | 5.12 | 5.12 |