Basic Information
ID: ALA4709781
Type: Binding
Description: Inhibition of TDO (unknown origin) assessed as reduction in L-kynurenine formation using L-tryptophan as substrate incubated for 30 mins microplate spectrophotometry analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4709781
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.29 | 2.10 | 2.10 |
| 438.24 | 0.42 | 0.42 |
| 323.74 | 2.76 | 2.76 |
| 415.45 | 1.49 | 1.49 |
| 275.27 | 2.04 | 2.04 |
| 310.70 | 2.09 | 2.09 |
| 319.28 | 1.74 | 1.74 |
| 354.35 | 0.69 | 0.69 |
| 320.26 | 1.95 | 1.95 |
| 343.70 | 2.54 | 2.54 |
| 354.71 | 2.60 | 2.60 |
| 357.73 | 2.84 | 2.84 |
| 293.26 | 2.18 | 2.18 |
| 309.71 | 2.70 | 2.70 |
| 315.29 | 1.92 | 1.92 |
| 343.70 | 2.54 | 2.54 |
| 309.71 | 2.70 | 2.70 |
| 300.28 | 1.91 | 1.91 |
| 362.15 | 3.49 | 3.49 |
| 344.16 | 3.35 | 3.35 |
| 327.70 | 2.84 | 2.84 |
| 289.29 | 2.35 | 2.35 |
| 293.26 | 2.18 | 2.18 |
| 333.30 | 1.83 | 1.83 |
| 345.14 | 2.74 | 2.74 |
| 332.32 | 2.00 | 2.00 |
| 326.32 | 2.59 | 2.59 |
| 345.69 | 2.97 | 2.97 |
| 320.26 | 1.95 | 1.95 |
| 309.71 | 2.70 | 2.70 |
| 315.29 | 1.92 | 1.92 |
| 343.31 | 1.22 | 1.22 |
| 377.71 | 3.71 | 3.71 |
| 357.73 | 2.84 | 2.84 |
| 345.69 | 2.97 | 2.97 |
| 327.70 | 2.84 | 2.84 |
| 276.26 | 1.44 | 1.44 |
| 373.42 | 1.79 | 1.79 |