Basic Information
ID: ALA4709982
Type: Binding
Description: Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation measured after 48 hrs by MTS assay
Organism: Homo sapiens
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA4709982
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.51 | 5.54 | 5.54 |
| 533.61 | 4.20 | 4.20 |
| 630.68 | 6.23 | 6.23 |
| 588.59 | 5.23 | 5.23 |
| 605.62 | 5.74 | 5.74 |
| 602.62 | 5.24 | 5.24 |
| 616.65 | 5.54 | 5.54 |
| 584.56 | 6.29 | 6.29 |
| 637.07 | 5.89 | 5.89 |
| 588.59 | 5.23 | 5.23 |
| 631.66 | 5.86 | 5.86 |
| 616.65 | 5.54 | 5.54 |
| 621.69 | 6.21 | 6.21 |
| 616.65 | 5.54 | 5.54 |
| 616.65 | 5.54 | 5.54 |
| 616.65 | 5.54 | 5.54 |
| 623.04 | 5.88 | 5.88 |
| 616.65 | 5.54 | 5.54 |
| 637.07 | 5.89 | 5.89 |
| 602.62 | 5.53 | 5.53 |
| 584.56 | 6.29 | 6.29 |
| 615.66 | 6.15 | 6.15 |
| 616.65 | 5.54 | 5.54 |
| 650.11 | 6.80 | 6.80 |
| 602.62 | 5.53 | 5.53 |
| 616.65 | 5.54 | 5.54 |
| 631.66 | 5.86 | 5.86 |
| 637.07 | 5.89 | 5.89 |
| 644.70 | 6.59 | 6.59 |
| 650.11 | 6.80 | 6.80 |
| 629.69 | 6.46 | 6.46 |
| 602.62 | 5.53 | 5.53 |
| 623.04 | 5.88 | 5.88 |
| 504.47 | 5.80 | 5.80 |
| 630.67 | 6.03 | 6.03 |
| 637.07 | 5.89 | 5.89 |
| 602.62 | 5.24 | 5.24 |
| 602.62 | 5.53 | 5.53 |