Basic Information
ID: ALA4710037
Type: Functional
Description: In vivo inhibition of KIF5B-RET V804M mutant fusion protein in BALB/c mouse implanted with KIF5B-RET V804M mutant fusion protein expressing mouse BaF3 cells assessed as reduction in RET phosphorylation at 30 to 50 mg/kg, iv administered daily for 7 days and measured 4 hrs post last dose by Western blot analysis
Organism: Mus musculus
Strain: BALB/c
Activity Charts
Bioactivity
Activity Types for Assay ALA4710037
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 602.62 | 5.53 | 5.53 |