Basic Information
ID: ALA4710041
Type: Functional
Description: Induction of apoptosis in KIF5B-RET V804M mutant fusion protein expressing mouse BaF3 cells implanted in BALB/c mouse assessed as increase in cleaved caspase-3 level at 30 to 50 mg/kg, iv administered once daily for 7 days measured 4 hrs post last dose by H and E staining based immunohistochemical analysis
Organism: Mus musculus
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA4710041
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 602.62 | 5.53 | 5.53 |