Assay Report Card

Basic Information

ID: ALA4710042

Type: Functional

Description: Induction of apoptosis in KIF5B-RET fusion protein expressing mouse BaF3 cells implanted in BALB/c mouse assessed as increase in cleaved caspase-3 level at 30 to 50 mg/kg, iv administered once daily for 7 days measured 4 hrs post last dose by H and E staining based immunohistochemical analysis

Organism: Mus musculus

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
602.625.535.53