Assay Report Card

Basic Information

ID: ALA4710046

Type: Functional

Description: Antitumor activity against KIF5B-RET V804M mutant fusion protein expressing mouse BaF3 cells implanted in BALB/c mouse assessed as tumor growth inhibition at 30 to 50 mg/kg, iv administered once daily for 7 days relative to control

Organism: Mus musculus

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
602.625.535.53