Basic Information
ID: ALA4710052
Type: Binding
Description: Protac activity at VHL/EGFR L858R/T790M mutant in human H1975 cells assessed as induction of degradation of EGFR at 333 nM incubated for 48 hrs measured after compound wash-out for 48 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4710052
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 995.31 | 8.74 | 8.74 |
| 1009.34 |