Basic Information
ID: ALA4710055
Type: Binding
Description: Protac activity at VHL/EGFR del19 mutant in human HCC827 cells assessed as induction of EGFR degradation at 33 nM incubated for 24 hrs measured following drug wash-out for 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HCC827
Activity Charts
Bioactivity
Activity Types for Assay ALA4710055
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 995.31 | 8.74 | 8.74 |
| 1009.34 |