Assay Report Card

Basic Information

ID: ALA4710075

Type: Binding

Description: Protac activity at VHL/EGFR L858R/T790M mutant in human H1975 cells assessed as maximal induction of degradation of EGFR incubated for 48 hrs by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
995.318.748.74
1009.34