Assay Report Card

Basic Information

ID: ALA4710079

Type: Binding

Description: Protac activity at VHL/EGFR del19 mutant in human HCC827 cells assessed as induction of EGFR degradation by measuring reduction in Akt phosphorylation at 3 nM incubated for 48 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HCC827

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
995.318.748.74