Basic Information
ID: ALA4710081
Type: Binding
Description: Protac activity at VHL/EGFR L858R/T790M mutant in human H1975 cells assessed as induction of degradation of EGFR by measuring reduction in Akt phosphorylation at 100 nM incubated for 48 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4710081
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 995.31 | 8.74 | 8.74 |