Basic Information
ID: ALA4710092
Type: Binding
Description: Protac activity at VHL/EGFR del19 mutant in human HCC827 cells assessed as induction of EGFR degradation at 0.033 uM pretreated with VHL ligand, VHL-Ac for 2 hrs followed by incubation with compound for 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HCC827
Activity Charts
Bioactivity
Activity Types for Assay ALA4710092
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 995.31 | 8.74 | 8.74 |