Assay Report Card

Basic Information

ID: ALA4710098

Type: Binding

Description: Protac activity at VHL/EGFR del19 mutant in human HCC827 cells assessed as induction of EGFR degradation at 0.1 to 0.3 nM precultured in medium without FBS followed by incubation with compound for 16 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HCC827

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
995.318.748.74