Basic Information
ID: ALA4710099
Type: Binding
Description: Protac activity at VHL/EGFR L858R/T790M mutant in human H1975 cells assessed as induction of degradation of EGFR at 100 to 333 nM precultured in medium without FBS followed by incubation with compound for 16 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4710099
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 995.31 | 8.74 | 8.74 |