Assay Report Card

Basic Information

ID: ALA4710428

Type: Binding

Description: Inhibition of Mycobacterium tuberculosis H37Rv DprE1 assessed as increase in trehalose monomycolates at 100 x MIC incubated for 24 hrs using [14C]acetate by TLC based metabolic labelling assay relative to control

Organism: Mycobacterium tuberculosis H37Rv

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
431.393.323.32
456.494.294.29
494.584.144.14
493.553.903.90
480.563.883.88
495.574.564.56