Assay Report Card

Basic Information

ID: ALA4710429

Type: Binding

Description: Inhibition of Mycobacterium tuberculosis H37Rv DprE1 assessed as increase in trehalose dimycolates at 10 x MIC preincubated for 24 hrs using [14C]acetate by TLC based metabolic labelling assay relative to control

Organism: Mycobacterium tuberculosis H37Rv

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
493.553.903.90
480.563.883.88
495.574.564.56
490.395.145.14
445.945.035.03