Basic Information
ID: ALA4710511
Type: Binding
Description: Inhibition of glycoprotein in VSV-G pseudotyped EBOV Mayinga infected in human HEK293T cells assessed as reduction in virus entry preincubated with pseudotyped virus for 1 hr followed by cell infection and measured after 48 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Ebolavirus
Strain: Mayinga
Cell type: HEK293T
Target: Unchecked(ALA612545)
Document: ALA4706564
Inhibition of glycoprotein in VSV-G pseudotyped EBOV Mayinga infected in human HEK293T cells assessed as reduction in virus entry preincubated with pseudotyped virus for 1 hr followed by cell infection and measured after 48 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4710511
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.24 | 5.18 | 5.18 |
| 295.42 | 2.47 | 2.47 |
| 308.47 | 2.38 | 2.38 |
| 281.40 | 2.08 | 2.08 |
| 293.45 | 3.62 | 3.62 |
| 322.49 | 2.77 | 2.77 |
| 294.44 | 1.99 | 1.99 |
| 293.45 | 3.48 | 3.48 |
| 308.47 | 2.38 | 2.38 |
| 352.48 | 2.52 | 2.52 |
| 306.49 | 3.44 | 3.44 |
| 307.48 | 3.87 | 3.87 |
| 279.42 | 3.23 | 3.23 |
| 366.50 | 2.91 | 2.91 |
| 292.47 | 3.05 | 3.05 |
| 267.41 | 3.09 | 3.09 |
| 293.45 | 3.48 | 3.48 |
| 324.47 | 1.35 | 1.35 |
| 307.48 | 4.01 | 4.01 |
| 321.51 | 4.26 | 4.26 |
| 293.45 | 1.56 | 1.56 |
| 380.53 | 3.30 | 3.30 |
| 281.44 | 3.48 | 3.48 |
| 320.52 | 3.83 | 3.83 |
| 335.54 | 2.74 | 2.74 |
| 293.45 | 3.62 | 3.62 |
| 279.42 | 3.23 | 3.23 |
| 370.54 | 3.56 | 3.56 |
| 321.51 | 4.40 | 4.40 |
| 239.36 | 2.31 | 2.31 |
| 335.53 | 4.65 | 4.65 |
| 321.51 | 2.35 | 2.35 |
| 308.47 | 2.43 | 2.43 |
| 280.41 | 1.65 | 1.65 |
| 329.91 | 3.62 | 3.62 |
| 351.54 | 2.10 | 2.10 |
| 322.49 | 2.77 | 2.77 |
| 321.51 | 4.40 | 4.40 |
| 352.52 | 2.13 | 2.13 |
| 307.48 | 4.01 | 4.01 |
| 384.56 | 3.95 | 3.95 |
| 321.51 | 2.35 | 2.35 |
| 309.45 | 2.86 | 2.86 |
| 307.48 | 1.95 | 1.95 |
| 295.47 | 3.87 | 3.87 |
| 253.39 | 2.70 | 2.70 |
| 279.42 | 3.23 | 3.23 |
| 307.48 | 1.95 | 1.95 |
| 323.48 | 1.32 | 1.32 |
| 336.52 | 3.16 | 3.16 |
| 343.94 | 3.87 | 3.87 |
| 267.41 | 3.09 | 3.09 |
| 338.49 | 1.74 | 1.74 |
| 294.44 | 2.04 | 2.04 |
| 293.45 | 3.48 | 3.48 |
| 398.59 | 4.34 | 4.34 |