Basic Information
ID: ALA4710715
Type: Binding
Description: Antagonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as inhibition of MDP-induced NFkappaB activation-mediated SEAP release at 5 uM preincubated for 3 hrs followed by MDP addition and measured after 20 hrs by spectrophotometric method relative to control
Organism: Homo sapiens
Cell type: HEK-Blue hNOD2
Activity Charts
Bioactivity
Activity Types for Assay ALA4710715
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 598.58 | 5.24 | 5.24 |
| 715.68 | 5.46 | 5.46 |
| 473.50 | 3.74 | 3.74 |
| 534.54 | 3.72 | 3.72 |
| 417.90 | 4.61 | 4.61 |
| 573.96 | 5.11 | 5.11 |
| 554.53 | 4.73 | 4.73 |
| 535.44 | 5.57 | 5.57 |
| 524.40 | 4.91 | 4.91 |
| 584.55 | 4.60 | 4.60 |
| 541.56 | 3.45 | 3.45 |
| 598.58 | 5.24 | 5.24 |
| 627.06 | 5.95 | 5.95 |
| 435.89 | 4.75 | 4.75 |
| 485.44 | 4.69 | 4.69 |
| 673.64 | 5.69 | 5.69 |
| 469.50 | 3.81 | 3.81 |
| 501.89 | 5.46 | 5.46 |
| 497.51 | 3.55 | 3.55 |
| 541.48 | 4.54 | 4.54 |
| 626.59 | 4.37 | 4.37 |
| 425.45 | 3.91 | 3.91 |
| 485.89 | 5.62 | 5.62 |
| 555.59 | 4.10 | 4.10 |
| 555.51 | 5.18 | 5.18 |
| 551.00 | 4.24 | 4.24 |
| 655.65 | 5.39 | 5.39 |
| 640.62 | 5.01 | 5.01 |
| 501.89 | 5.21 | 5.21 |
| 507.95 | 4.39 | 4.39 |
| 452.34 | 5.26 | 5.26 |
| 673.64 | 5.69 | 5.69 |
| 401.44 | 4.09 | 4.09 |
| 512.49 | 4.96 | 4.96 |
| 573.96 | 4.86 | 4.86 |
| 663.04 | 6.19 | 6.19 |
| 451.45 | 4.97 | 4.97 |
| 526.52 | 5.60 | 5.60 |
| 559.93 | 5.02 | 5.02 |
| 637.66 | 5.44 | 5.44 |
| 540.50 | 4.70 | 4.70 |
| 516.55 | 3.58 | 3.58 |
| 584.55 | 4.60 | 4.60 |
| 557.50 | 4.34 | 4.34 |
| 568.55 | 5.37 | 5.37 |
| 548.57 | 4.36 | 4.36 |