Basic Information
ID: ALA4711165
Type: Binding
Description: Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forskolin and genistein addition for 30 mins by fluorescence based assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CFBE41o-
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA4706592
Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forskolin and genistein addition for 30 mins by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4711165
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.61 | 6.23 | 6.23 |
| 498.56 | 5.45 | 5.45 |
| 552.53 | 6.34 | 6.34 |
| 513.58 | 5.47 | 5.47 |
| 514.63 | 6.16 | 6.16 |
| 498.56 | 5.45 | 5.45 |
| 547.43 | 6.20 | 6.20 |
| 524.60 | 5.87 | 5.87 |
| 512.54 | 5.17 | 5.17 |
| 550.66 | 7.17 | 7.17 |
| 483.55 | 5.46 | 5.46 |
| 486.52 | 5.58 | 5.58 |
| 527.56 | 4.24 | 4.24 |
| 544.63 | 7.11 | 7.11 |
| 540.60 | 5.62 | 5.62 |
| 406.46 | 4.41 | 4.41 |
| 469.52 | 4.84 | 4.84 |
| 498.56 | 5.45 | 5.45 |
| 526.61 | 6.23 | 6.23 |
| 544.63 | 7.11 | 7.11 |
| 477.54 | 3.68 | 3.68 |
| 518.98 | 5.80 | 5.80 |
| 528.59 | 5.46 | 5.46 |
| 422.46 | 3.78 | 3.78 |
| 406.46 | 4.08 | 4.08 |
| 537.64 | 6.04 | 6.04 |
| 539.66 | 6.29 | 6.29 |
| 528.59 | 5.46 | 5.46 |
| 512.54 | 5.14 | 5.14 |
| 533.01 | 6.10 | 6.10 |
| 525.59 | 4.80 | 4.80 |
| 538.67 | 7.17 | 7.17 |
| 547.43 | 6.20 | 6.20 |