Basic Information
ID: ALA4711208
Type: Binding
Description: Antagonist activity at AhR in human HepG2 cells co-transfected with pSELECT-zeo-Lucia and CYP1A1 assessed as inhibition of FICZ-induced receptor transactivation at 10 uM incubated for 24 hrs by luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Aryl hydrocarbon receptor(ALA3201)
Document: ALA4706594
Antagonist activity at AhR in human HepG2 cells co-transfected with pSELECT-zeo-Lucia and CYP1A1 assessed as inhibition of FICZ-induced receptor transactivation at 10 uM incubated for 24 hrs by luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4711208
RUmax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.40 | 4.11 | 4.11 |
| 317.39 | 4.50 | 4.50 |
| 275.35 | 4.28 | 4.28 |
| 382.26 | 4.95 | 4.95 |
| 353.81 | 4.08 | 4.08 |
| 275.35 | 4.28 | 4.28 |
| 295.77 | 4.62 | 4.62 |
| 333.39 | 3.73 | 3.73 |
| 342.40 | 4.67 | 4.67 |
| 267.35 | 4.03 | 4.03 |
| 340.22 | 4.73 | 4.73 |
| 295.77 | 4.62 | 4.62 |
| 321.35 | 4.33 | 4.33 |
| 337.35 | 3.56 | 3.56 |
| 314.39 | 4.75 | 4.75 |
| 341.41 | 5.13 | 5.13 |
| 411.46 | 5.27 | 5.27 |
| 281.38 | 4.33 | 4.33 |
| 279.31 | 4.11 | 4.11 |
| 342.40 | 3.92 | 3.92 |
| 317.43 | 5.26 | 5.26 |
| 340.22 | 4.73 | 4.73 |
| 316.36 | 3.47 | 3.47 |
| 279.31 | 4.11 | 4.11 |
| 398.26 | 4.19 | 4.19 |
| 337.81 | 4.84 | 4.84 |
| 344.37 | 3.39 | 3.39 |
| 359.35 | 4.39 | 4.39 |