Basic Information
ID: ALA4711500
Type: Binding
Description: Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrate addition measured after 20 mins by fluorescence analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4711500
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 477.05 | 5.09 | 5.09 |
| 252.27 | 2.92 | 2.92 |
| 349.43 | 4.21 | 4.21 |
| 324.38 | 4.01 | 4.01 |
| 282.30 | 2.93 | 2.93 |
| 337.42 | 4.07 | 4.07 |
| 280.32 | 3.61 | 3.61 |
| 266.30 | 3.22 | 3.22 |
| 363.46 | 4.60 | 4.60 |
| 281.31 | 2.81 | 2.81 |
| 324.38 | 4.01 | 4.01 |
| 296.32 | 3.23 | 3.23 |
| 326.35 | 3.24 | 3.24 |
| 266.30 | 3.22 | 3.22 |
| 268.27 | 2.63 | 2.63 |
| 335.40 | 3.82 | 3.82 |
| 323.35 | 3.18 | 3.18 |
| 282.30 | 2.93 | 2.93 |