Assay Report Card

Basic Information

ID: ALA4711509

Type: Binding

Description: Modulation of MRP1 in dog MDCK-MRP1 cells assessed as inhibition of calcein-AM transport using calcein-AM as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fluorescence analysis

Organism: Canis lupus familiaris

Cell type: MDCK-MRP1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
528.675.755.75
690.796.796.79
564.716.886.88
812.608.048.04
610.827.707.70
604.777.327.32
544.675.745.74
654.838.488.48
570.756.926.92
593.546.496.49
559.645.645.64
723.707.827.82
714.866.536.53
542.706.146.14
744.806.336.33
549.096.386.38
598.817.707.70
532.645.875.87