Basic Information
ID: ALA4711512
Type: Binding
Description: Modulation of P-gp1 in dog MDCK-MDR1 cells assessed as induction of ATP cell depletion preincubated for 2 hrs followed by substrate addition and measured after 10 mins in dark by ATPlite luminescence assay
Organism: Canis lupus familiaris
Cell type: MDCK-MDR1
Activity Charts
Bioactivity
Activity Types for Assay ALA4711512
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 528.67 | 5.75 | 5.75 |
| 690.79 | 6.79 | 6.79 |
| 564.71 | 6.88 | 6.88 |
| 812.60 | 8.04 | 8.04 |
| 610.82 | 7.70 | 7.70 |
| 604.77 | 7.32 | 7.32 |
| 544.67 | 5.74 | 5.74 |
| 654.83 | 8.48 | 8.48 |
| 570.75 | 6.92 | 6.92 |
| 593.54 | 6.49 | 6.49 |
| 559.64 | 5.64 | 5.64 |
| 723.70 | 7.82 | 7.82 |
| 714.86 | 6.53 | 6.53 |
| 542.70 | 6.14 | 6.14 |
| 744.80 | 6.33 | 6.33 |
| 549.09 | 6.38 | 6.38 |
| 598.81 | 7.70 | 7.70 |
| 532.64 | 5.87 | 5.87 |