Basic Information
ID: ALA4711514
Type: Binding
Description: Modulation of P-gp1 in dog MDCK-MDR1 cells assessed as potentiation of doxorubicin-induced cytotoxicity at 500 to 1000 nM preincubated for 1 day followed by removal of medium and later subsequently incubated with compound and doxorubicin and measured after 48 hrs by MTT assay
Organism: Canis lupus familiaris
Cell type: MDCK-MDR1
Activity Charts
Bioactivity
Activity Types for Assay ALA4711514
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 714.86 | 6.53 | 6.53 |