Basic Information
ID: ALA4711531
Type: Binding
Description: Induction of P-gp mediated transport of [3H]-digoxin transport across apical to basolateral side in human Caco2 cells at 100 nM compound preincubated with saliva for 5 mins followed by incubation with gastrointestinal fluid for 2 hrs followed by incubation with duodenal fluid for 2 hrs prior to cell line addition and measured after 2 hrs by liquid scintillation method
Organism: Homo sapiens
Cell type: Caco-2
Activity Charts
Bioactivity
Activity Types for Assay ALA4711531
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 714.86 | 6.53 | 6.53 |