Basic Information
ID: ALA4711967
Type: Functional
Description: Invivo antagonist activity at GPR52 in HdhQ140 knock-in mouse model assessed as reduction in mHTT aggregate levels in striatum in presence of 4C9 antibody labelled with D2 fluorophore at 5 mg/kg, iv QD for 4 weeks by TR-FRET analysis
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4711967
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 226.28 | 3.65 | 3.65 |