Assay Report Card

Basic Information

ID: ALA4711969

Type: Functional

Description: Invivo antagonist activity at GPR52 in HdhQ140 knock-in mouse model assessed as reduction in mHTT aggregate levels in cortex in presence of 4C9 antibody labelled with D2 fluorophore at 5 mg/kg, iv QD for 4 weeks by TR-FRET analysis

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
226.283.653.65