Basic Information
ID: ALA4712220
Type: Binding
Description: Protac activity at CRBN/MEK2 in human HT-29 cells assessed as induction of MEK1 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA4712220
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 764.50 | 3.61 | 3.61 |
| 984.76 | 3.69 | 3.69 |
| 848.66 | 5.95 | 5.95 |
| 940.71 | 3.67 | 3.67 |
| 778.53 | 4.00 | 4.00 |
| 998.79 | 4.03 | 4.03 |
| 834.63 | 5.56 | 5.56 |
| 806.58 | 4.78 | 4.78 |