Basic Information
ID: ALA4712243
Type: Binding
Description: Protac activity at CRBN/MEK1/2 in human HT-29 cells assessed as induction of MEK1/2 degradation pre-incubated with MEK1/2 inhibitor PD0325901 for 2 hrs followed by compound addition at 0.3 uM and further incubated for 8 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA4712243
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 984.76 | 3.69 | 3.69 |