Basic Information
ID: ALA4712244
Type: Binding
Description: Protac activity at VHL/MEK1/2 in human HT-29 cells assessed as induction of MEK1/2 degradation pre-incubated with MEK1/2 inhibitor PD0325901 for 2 hrs followed by compound addition at 0.1 uM and further incubated for 8 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA4712244
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1090.10 | ||
| 1104.13 |