Basic Information
ID: ALA4712250
Type: Binding
Description: Protac activity at CRBN/MEK1/2 in human HT-29 cells assessed as induction of MEK1/2 degradation pre-incubated with CRBN ligand pomalidomide for 2 hrs followed by compound addition at 0.3 uM and further incubated for 8 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HT-29
Target: Unchecked(ALA612545)
Document: ALA4706631
Protac activity at CRBN/MEK1/2 in human HT-29 cells assessed as induction of MEK1/2 degradation pre-incubated with CRBN ligand pomalidomide for 2 hrs followed by compound addition at 0.3 uM and further incubated for 8 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4712250
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 984.76 | 3.69 | 3.69 |