Basic Information
ID: ALA4712903
Type: Binding
Description: Inhibition of full-length human OGA expressed in Expi293 (HEK293) cells using 4-methylumbelliferyl-N-acetyl-beta-D-glucosaminide dihydrate as fluorogenic substrate preincubated with enzyme followed by substrate addition and measured every 5 mins for 60 mins by fluorescence based analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4712903
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.42 | 2.75 | 2.75 |
| 297.41 | 1.88 | 1.88 |
| 296.42 | 3.37 | 3.37 |
| 297.41 | 2.76 | 2.76 |
| 284.36 | 1.97 | 1.97 |
| 286.38 | 2.06 | 2.06 |
| 298.39 | 2.09 | 2.09 |
| 283.38 | 2.72 | 2.72 |
| 332.50 | 1.76 | 1.76 |
| 297.41 | 2.76 | 2.76 |