Basic Information
ID: ALA4713240
Type: Binding
Description: Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr followed by anti-pSTAT1 antibody addition and measured after 30 mins by Lanthascreen TR-FRET assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA4706658
Inhibition of recombinant JAK2 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr followed by anti-pSTAT1 antibody addition and measured after 30 mins by Lanthascreen TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4713240
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 425.51 | 1.98 | 1.98 |
| 349.44 | 2.74 | 2.74 |
| 407.52 | 3.40 | 3.40 |
| 411.48 | 2.96 | 2.96 |
| 383.88 | 3.26 | 3.26 |
| 377.49 | 3.39 | 3.39 |
| 402.50 | 3.26 | 3.26 |
| 407.52 | 3.40 | 3.40 |
| 411.94 | 3.90 | 3.90 |
| 363.47 | 3.00 | 3.00 |
| 402.50 | 3.26 | 3.26 |
| 411.48 | 2.96 | 2.96 |
| 407.52 | 3.26 | 3.26 |
| 383.88 | 3.26 | 3.26 |
| 389.50 | 3.53 | 3.53 |
| 407.52 | 3.40 | 3.40 |
| 407.52 | 3.40 | 3.40 |
| 393.49 | 3.01 | 3.01 |
| 423.95 | 4.18 | 4.18 |
| 411.94 | 4.04 | 4.04 |
| 411.94 | 4.04 | 4.04 |
| 377.49 | 3.39 | 3.39 |
| 393.49 | 3.01 | 3.01 |
| 393.49 | 3.01 | 3.01 |
| 415.90 | 3.60 | 3.60 |
| 411.94 | 4.04 | 4.04 |
| 411.94 | 4.04 | 4.04 |
| 407.52 | 3.40 | 3.40 |
| 388.48 | 2.87 | 2.87 |
| 411.94 | 4.04 | 4.04 |
| 411.94 | 4.04 | 4.04 |
| 447.58 | 4.32 | 4.32 |
| 414.51 | 3.40 | 3.40 |
| 397.91 | 3.78 | 3.78 |
| 419.53 | 3.54 | 3.54 |
| 407.52 | 3.40 | 3.40 |
| 423.52 | 3.02 | 3.02 |
| 393.49 | 3.14 | 3.14 |
| 423.95 | 4.18 | 4.18 |
| 411.94 | 4.04 | 4.04 |
| 419.53 | 3.54 | 3.54 |
| 419.53 | 3.54 | 3.54 |